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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHC3 All Species: 18.18
Human Site: S254 Identified Species: 44.44
UniProt: Q92529 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92529 NP_058544.3 594 64056 S254 N H H M R S I S F A S G G D P
Chimpanzee Pan troglodytes XP_520118 594 64067 S254 N H H M R S I S F A S G G D P
Rhesus Macaque Macaca mulatta XP_001089267 598 64694 S254 N H H M R S I S F A S G G D P
Dog Lupus familis XP_533553 444 48696 G139 H I L E C C D G L A Q D V I G
Cat Felis silvestris
Mouse Mus musculus Q61120 474 52188 L169 I L E C C D G L A Q D V I G S
Rat Rattus norvegicus O70143 594 64082 S254 N H H M R S I S F A S G G D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512200 548 59956 E243 Q R A C H I L E C C E A Q S V
Chicken Gallus gallus XP_428819 632 69780 S276 N H H M Q S I S F A S G G D P
Frog Xenopus laevis Q8AY68 465 51711 E160 G G D P D T A E Y V A Y V A K
Zebra Danio Brachydanio rerio XP_002665883 393 43159 Q88 E C S D G L A Q D V I S T I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.4 67.5 N.A. 73 91 N.A. 47.8 67.7 45.2 42.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 97.8 70.3 N.A. 75.5 93.9 N.A. 61.2 76.9 57.9 49.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 0 100 N.A. 0 93.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 0 100 N.A. 6.6 100 20 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 20 0 10 60 10 10 0 10 0 % A
% Cys: 0 10 0 20 20 10 0 0 10 10 0 0 0 0 0 % C
% Asp: 0 0 10 10 10 10 10 0 10 0 10 10 0 50 0 % D
% Glu: 10 0 10 10 0 0 0 20 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 10 0 10 10 0 0 0 50 50 10 20 % G
% His: 10 50 50 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 0 0 10 50 0 0 0 10 0 10 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 10 0 0 10 10 10 10 0 0 0 0 0 0 % L
% Met: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 50 % P
% Gln: 10 0 0 0 10 0 0 10 0 10 10 0 10 0 0 % Q
% Arg: 0 10 0 0 40 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 50 0 50 0 0 50 10 0 10 10 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 20 0 10 20 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _